We are broadly interested in plant-microbe interactions. However, we focus on powdery mildew diseases caused by fungi in the Erysiphaceae; primarily the Arabidopsis powdery mildew disease caused by Golovinomyces cichoracearum and the barley powdery mildew disease caused by Blumeria graminis f. sp. hordei. Some of the questions of interest in the lab are what are the mechanisms of disease resistance deployed by plants against this group of pathogens and what plant processes support optimal disease development by these obligate biotrophic pathogens. In addressing the first question, we have studied “non-host” resistance exhibited by Arabidopsis against the barley powdery mildew and the role of the plant cell wall in restricting powdery mildew host range.  With the advent of whole genome sequencing of powdery mildews, opportunities to study pathogen determinants of disease development open up. Initially, we will characterize powdery mildew effectors required for successful disease development and the host targets of these effectors.  All these approaches provide complementary strategies for manipulating disease resistance in plants to standard Resistance gene-based methods.